Located in the Department of Molecular and Cellular Biology at the University of Adelaide, Australia, our research focuses on the host response, basic molecular virology and pathogenic mechanisms of disease for viruses belonging to the flaviviridae family, including Hepatitis C Virus (HCV), Dengue Virus (DENV) and Zika Virus (ZIKV).
Learn more about our research and areas of study below
Infection of the cell results in activation of an innate immune response and expression of antiviral interferon stimulated genes (ISGs). We are interesed in which ISGs control viral infecion and their machansim of action.
170 million: that’s how many people around the world are infected with HCV. For many of those people, this infection will result in significant liver disease and cancer. HCV infection is now the leading indication for liver transplantation in many countries including Australia
Currently an epidemic in the Americas, ZIKV can cause microcephaly in newborns. We are investigating the response of the placenta and the neonatal brain to ZIKV infection in the hope of understanding ZIKV pathogenesis.
Responsible for many deaths worldwide in developing countries, capable of causing dengue haemorhagic fever and shock syndrome